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貨號 產品名 純度
A324075 現貨 GSK 650394

GSK 650394是一種 SGK1 和 SGK2 抑制劑,IC50 分別為 62 nM 和 103 nM,能夠抑制流感病毒復制,可用于多種疾病研究。

≥99%
A759585 現貨 EMD638683

EMD638683是一種高度選擇性的SGK1抑制劑,IC50值為3 μM。

≥99%
A521108 現貨 URMC-099

URMC-099是一種口服生物可利用、腦滲透性強的混合譜激酶 3(MLK3)抑制劑,IC50 為 14 nM,能夠抑制小膠質細胞中 LPS 引起的 TNFα 釋放、HIV-1 Tat 引起的細胞因子釋放及小鼠腦內磷酸化 JNK 上調。

≥99%
A138869 現貨 RO-3306

RO-3306是一種強效且選擇性的 CDK1 抑制劑,對 CDK1/cyclin B1 的 Ki 值為 35 nM,選擇性是 CDK2/cyclin E 和 CDK4/cyclin D 的 10 倍和 50 倍以上。

≥99%
A1467750 現貨 HaloPROTAC-E

HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded.

≥99%
A1549267 SGK1-IN-4

97%
A1549573 SGK1-IN-2

98%
A1602303 SGK1-IN-3

98%
A1807668 SI-113

98%
A290613 CKI-7 free base

99%
A1550518 Hu7691 free base

98%
A1602519 PF-4950834

98%
A1550519 Hu7691

98%
A497934 EMD638683 R-Form

EMD638683 R-form is the R-form of EMD638683, which is a highly selective SGK1 inhibitor with IC50 of 3 μM.

99%
A570514 EMD638683 S-Form

EMD638683 S-form is the S-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.

99%
A1144070 SGK1-IN-1

SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM.

99%
A1339749 BN201

98%
A1209727 BRD7389

BRD7398 is a RSK kinase inhibitor that induces insulin expression and differentiation of pancreatic alpha into beta cells. It inhibits RSK1, RSK2 and RSK3 with IC50 values of 1.5, 2.4 and 1.2 uM, respectively.

99%
A939823 AT13148

AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively.

99%
A332905 CKI-7

98+%
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